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butabarbital will reduce the level or effect of doxorubicin liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.butabarbital will reduce the level or impact of sufentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.butabarbital will reduce the level or effect of pimozid